The correlations between exosomal miR-940 and pathophysiological parameters in breast cancer patients are shown in Figure 5C, which showed that exosomal miR-940 levels were significantly lower in HER2/neu-positive patients than in HER2/neu-negative patients (median copy number: 9.43×1011 vs. 1.46×1012, P=0.017). This evidence concerns the gene ERBB2 and breast carcinoma.