Albumin is another versatile and stable biomaterial for nanoparticle synthesis and tumor therapy, as albumin can specifically bind to receptors overexpressed in cancer cells, such as gp60 (60 kDa glycoprotein receptor) and SPARC (secreted protein, acidic and rich in cysteine) and actively increase the internalization of nanoparticles (143). The gene discussed is ALB; the disease is neoplasm.