Additionally, the docetaxel treatment found significantly higher apoptotic cells compared to USP8 overexpression in both PCa cell lines (ovUSP8 vs. docetaxel: DU145, 1.3 ± 0.2% vs. 7.15 ± 0.28%, P value = 0.0006; PC3, 2.1 ± 0.4% vs. 15.11 ± 0.24%, P value ≤0.0001). The gene discussed is USP8; the disease is posterior cortical atrophy.