ROC analysis found that overexpression of AC020558.2, ZNF32-AS2, AP4B1-AS1, AL355488.1, AC109460.3, SNHG1, C3orf35, LMNTD2-AS1, and AL365330.1 had significant value for the evaluation of the 1-, 3- and 5-year OS and PFI in PC patients (Figure 10 and Figure S6). The gene discussed is AP4B1; the disease is pachyonychia congenita.