As shown in Supplementary Figure 2, up-regulated CD44, DPP4, SAT1 and NCOA4 were found in AML patients, while CHAC1, CISD1, SLC7A11, AIFM2, G6PD, and ACSF2 were down-regulated in AML patients. The gene discussed is SLC7A11; the disease is acute myeloid leukemia.