TGFB1 and lung carcinoma: Mounting evidence revealed that the aberrant expression of circRNAs is implicated in the invasion and metastasis of lung cancer —for example, circPTK2 acts a sponge for miR-429/miR-200b-3p, thus promoting TGF-β-induced EMT via TIF1γ and the invasiveness of NSCLC cell (15).