Of note, GBM cancer cells were also observed to display a high expression of the above-mentioned fatty acid synthesis and desaturation genes (FASN, SCD and FADS2) relative to most other cell types in our scRNA-seq data set (Supplementary Figure S2C), with the exception of oligodendrocytes and myeloid cells, for which SCD was also highly expressed, in agreement with prior reports (33). Here, FADS2 is linked to glioblastoma.