We observed that both newly diagnosed and recurrent GBM cells were slightly sensitive to FADS2 inhibition and insensitive to SCD inhibition (Figures 5C-F), which is in line with our finding that glioblastoma cells display high FADS2 mono-desaturation activity leading to sapienate and polyunsaturated fatty acid production. This evidence concerns the gene FADS2 and glioblastoma.