In the 3-methylcholanthrene/butylated hydroxytoluene animal model, which is an inflammation-dependent priming-promoting model, chronic persistent alveolar hypoxia increased the expression of epidermal growth factor receptor (EGFR), fibroblast growth factor receptor 2, and platelet-derived growth factor receptor, which are known to promote tumor growth and angiogenesis. Here, EGFR is linked to neoplasm.