Firstly, we found that A549 cells were sensitive to ionizing irradiation, and 6Gy irradiation partially inhibited their growth, while the treatment with a conditioned medium of radiation-activated CAFs could reverse the apoptosis of irradiated A549 cells and promote their growth (Figure 4C), thus reflecting the “apoptosis protection” effect of radiation-activated CAFs on cancer cells. This evidence concerns the gene TBX1 and cancer.