WT1 and Nephroblastoma: In the earlier study, Predisposition loci at 11p13(WT1),17q21(FWT1), 19q13 (FWT2) and 11p15 were identified by genetic linkage studies of familial Wilms tumor (9–11).With the development of modern genetic technology, the diverse genetic landscape of Wilms tumor is now beginning to be unveiled.