After excluding patients who were diagnosed with ovarian cancer at the age <18 years old or >80 years old (n = 16,241), patients at M0 stage (n = 86,710), patients who lost the data on surgery (n = 12), CA125 (n = 1,556) or who were unclear about whether they received surgery or not (n = 681), 5,442 patients were included. The gene discussed is MUC16; the disease is ovarian carcinoma.