PDCD1 and familial pancreatic carcinoma: For example, a phase II study is ongoing to evaluate the combination of vitamin D with PD-1 inhibitors and radiation in a patient with advanced and refractory cervical cancer, endometrial carcinoma, or uterine sarcoma (NCT03192059), and treatment with vitamin D in association with chemo- or anti-PD-1-therapies are currently evaluated for patients with pancreatic cancer (NCT02754726).