The gene fusions, identified by ADx in samples lacking FISH confirmation (sample 41–52, Table 2), were in line with the patient’s diagnosis: KIAA1549-BRAF in astrocytoma [23], ALK or NTRK translocations in thyroid papillary carcinoma [24], lung adenocarcinoma [25] as well as sarcomas NOS [26]. The gene discussed is ALK; the disease is lung adenocarcinoma.