Recently, Gallazzi et al. [149] demonstrated that NK cells isolated from peripheral blood of PCa patients are polarized towards the CD56brightCD9+CD49a+CXCR4+ decidual-like phenotype and exhibit pro-angiogenic functions, inducing tube formation by endothelial cells, due to increased production of VEGF, CXCL8, CXCL12 by NK cells and their ability to polarize macrophages toward the M2-like/TAM phenotype (Figure 2O) [149]. The gene discussed is CXCL12; the disease is posterior cortical atrophy.