By performing NK cell-PCa cells co-culturing experiments, the authors showed that PCa cancer cells support the expression of ILT2/LILRB inhibitory receptor, together with downregulation of NKG2D, NKp46, and CD16 on NK cells, negatively impacting on NK-tumor cell recognition (Figure 2K) [144]. This evidence concerns the gene KLRK1 and posterior cortical atrophy.