Moreover, multivariate diagnostic analysis of the methylation status of WIF1, Sostdc1, and DACT2 showed up to 91% specificity and 100% sensitivity in discriminating breast cancer (invasive and non-invasive) from benign tumours and controls and may be a complementary tool for breast cancer diagnosis (Rajkumar et al., 2022). Here, SOSTDC1 is linked to breast carcinoma.