IL6 and Sepsis: VD supplementation can reduce the levels of TNF-α and IL-6, improve the coagulation parameters of disseminated intravascular coagulation, and enhance the induction of cathelicidin and B defensin in animal models of sepsis, thereby restricting the inflammatory attack of sepsis on multiple organs throughout the body, including the adrenal cortex (Olejarova et al., 2019).