ITGA2 and colorectal carcinoma: The mRNA expression level of ITGA2 has been found to be significantly higher in gastric cancer tissues compared to normal tissues (Chuang et al., 2018), is closely associated with other cancers such as pancreatic cancer and CRC, and therefore could be a potential therapeutic target for these cancers (Sakthianandeswaren et al., 2011; Ferraro et al., 2014; Li et al., 2021a).