KRAS and familial pancreatic carcinoma: A recent study found that miR-143-3p was significantly more expressed in MSC-derived exosomes than in exosomes from a human pancreatic cancer cell line (CFPAC-1) and could regulate KRAS, which is a key regulator and predictor of pancreatic cancer (Buscail et al., 2020; Wang et al., 2021b; Luo, 2021)and synergistically promote apoptosis and inhibit cell growth, invasion, and migration.