Comparatively, the effect size outperformed the most potent biomarkers in CAD such as troponin (HR of 1.47 in 10-year follow-up), coronary artery calcium (HR of 2.35 in 10-year follow-up), B-type natriuretic peptide (HR of 1.24 in 3-year follow-up), and high-sensitivity C-reactive protein (HR of 1.47 in 3-year follow-up).35 The gene discussed is CRP; the disease is coronary artery disorder.