A multivariate Cox regression analysis based on age, sex, ACCI, fibrinogen, CRP, LVEF, aspirin, clopidogrel, ACEI/ARB, β-blocker, hypertension, and D-dimer indicated that plasma D-dimer [HR: 1.071, 95% CI: 1.013–1.133, p < 0.017], ACCI [HR: 1.264, 95% CI: 1.141–1.400, p < 0.001], LVEF [HR: 1.069, 95% CI: 1.026–1.114, p = 0.001], aspirin [HR: 0.604, 95% CI: 0.369–0.990, p = 0.046], ACEI/ARB [HR: 0.661, 95% CI: 0.457–0.956, p = 0.028], and CCB [HR: 1.484, 95% CI: 1.018–2.164, p = 0.040] were independent risk factors for MACEs. The gene discussed is CRP; the disease is hypertensive disorder.