Except for the topics like “Diabetic cardiomyopathy,” “Cardiomyopathy” and “Diabetes” that we searched for, “Apoptosis,” “Oxidative stress” and “Fibrosis” have a higher frequency, “Forkhead box protein O1,” “Heart failure with preserved ejection fraction,” “Dapagliflozin,” “Thioredoxin,” “Mitochondria dysfunction,” “Glucose,” “Pyroptosis,” “Cardiac fibroblast” and “Long non-coding RNA” have potential research prospects. Here, FOXO1 is linked to heart failure.