Also, Kosar et al. showed that the increase in serum CA 125 levels in 35 patients with HF correlates with TNF-α (r = 0.624, p < 0.001), IL-6 (r = 0.671, p < 0.001), and IL-10 (r = 0.545, p < 0.001) (16). This evidence concerns the gene TNF and hydrops fetalis.