To our knowledge, PALMD is not released to the circulation.1 By contrast, we investigated whether the IL6 polymorphism could have an effect on the circulating levels of the cytokine in our patients, as it is described for coronary artery disease (21), by measuring IL-6 levels in 76 serum samples selected according to rs1800795 genotype. This evidence concerns the gene IL6 and coronary artery disorder.