,7 In the case of men, T. vaginalis secretes a protein homologous to human macrophage migration inhibitory factor (MIF) which has proinflammatory properties, and with combination of chronic inflammation, trichomoniasis can have an impact on the host immune system regulation and can play a role in the increased risk of prostate cancer.3 This evidence concerns the gene MIF and Trichomonas vaginitis urogenital infection.