However, OS pigs expressed less IL1A and more CXCR2 and IL18 compared to MC pigs while αGCOS pigs upregulated CCL5, CCR3, IL17A, FASLG, and IL2RB. A KEGG analysis of genes that were differentially expressed between MC and αGCOS pigs at the p < 0.1 level found enrichment of pathways involved in T helper 17 cell differentiation (IL1B, IL2RB, IL2RG, IL4, IL4R, IL17A, IL17F, IL21, IL23A, IL27) and anti-influenza immune responses (FASL, IL1, IL1B, IL12, CCL5). The gene discussed is IL18; the disease is influenza.