miR-375-3p upregulation is deemed to reduce the production of IL-1β and IL-6 in ECs in atopic dermatitis [57], and miR-375-3p upregulation in endothelial progenitor cells-isolated extracellular vesicles ameliorates sepsis in rats, as evidenced by alleviated pathological damage and decreased apoptosis, inflammatory responses, and oxidative stress in rat myocardial tissue [58], indicating the beneficial role of miR-375-3p in cell survival. The gene discussed is IL6; the disease is atopic eczema.