A more accurate characterization of more immature haematopoietic progenitors showed that CD123 expression was observed up to lymphomyeloid-committed progenitor (LMPP), haematopoietic stem cells and multipotent progenitors (HSC-MPPs) and, last, haematopoietic stem cells (HSC), with a significantly higher percentage of CD123+ cells in AML BM samples than in BM samples from HDs (Fig. 1D). Here, IL3RA is linked to acute myeloid leukemia.