ENSG00000309702 and neoplasm: In this study, we reported the identification of melanoma-specific lncRNAs and investigated the molecular and biological functions of OUM1. Microarrays and RACE assays confirmed a novel isoform of LOC100505912 is a noncoding transcript in UM, and named OUM1. We clearly demonstrate that PTPRZ1 contributes to tumor growth and metastasis as the downstream target of OUM1 and is considered a novel oncogene in UM development.