According to diagnostic indications for the VENTANA PD-L1 (SP142) Assay by ROCHE VENTANA, cutoff score for TNBC is ≥ 1% IC; whereas ≥ 50% TC or ≥ 10% IC for non-small cell lung cancer and ≥ 5% IC for urothelial carcinoma [23, 24]. Here, CD274 is linked to urothelial carcinoma.