Finally, nine genes (ACAA1, ACOT9, NCAPH2, NTHL1, CROT, ACSM3, SMS, EPHX2, and PON2) were used to construct a risk-scoring prognostic model (Fig. 1f,g, Table 1), which distinguished laryngeal cancer samples as high or low risk (Fig. 1h,i). This evidence concerns the gene PON2 and laryngeal carcinoma.