For instance, carrier frequency for P/LP variants in the hypertrophic cardiomyopathy gene MYBPC3 was eight-fold higher among Indians (0.41%) compared to Chinese (0.05%), attributed to the significantly higher frequency of MYBPC3 c.1790G > A (p.Arg597Gln) variant (Indian: 0.31% vs Chinese: 0%, p = 9.38 × 10−4). Here, MYBPC3 is linked to hypertrophic cardiomyopathy.