Univariate analysis showed that lymph node metastasis, T staging, Ki-67 level, preoperative CTCs karyotype, postoperative CTCs karyotype, and postoperative CTC count were significantly associated with PFS (P < 0.05), while age, gender, tumor diameter, and preoperative CTC count were not significant for prognosis (P > 0.05). Here, MKI67 is linked to metastatic malignant neoplasm in the lymph nodes.