Moreover, as IL-6 plays critical roles in the carcinogenesis of series types of cancer, such as hematologic tumors, gastrointestinal cancers, and urogenital neoplasms, whether decreased RIG-I-mediated vicious augment of IL-6 response is a common mechanism for IL-6-promoted malignancies may raise interesting future work in this field. This evidence concerns the gene IL6 and cancer.