In unpaired samples, the expression levels of CYP4F26P, LINC02178, TMEM99, and PTCSC2 were higher in cancer tissues than those in adjacent normal tissues (p < 0.001), and the expression levels of MIR22HG and SRP14-AS1 were higher in adjacent normal tissues than those in cancer tissues (all p < 0.001). The gene discussed is SRP14; the disease is cancer.