CRP and infection: A more recent study of Lemiengre et al. [10] showed that systematic POC CRP without guidance in comparison to usual care did not influence antibiotic prescribing in children with acute non-severe infections in primary care, and a Norwegian study [49], which took place in out-of-hours services, found that pre-consultation screening with CRP in children with fever and/or respiratory symptoms did not significantly affect the prescription of antibiotics or referral to hospital.