NRBF2 and glioblastoma: In addition to the GBM orthotopic xenograft mouse model, the two most commonly used GBM cell lines (U-87 MG and A172) and three patient-derived primary GBM cell lines (BCL20-HP02, BCL21-HP03, and GSC11) were used to confirm the general alteration in the pattern of nrbf2 expression after irradiation.