Given the appearance of cardiac cell damage and death in cMKO mice during DCM (Fig. 1n, o) and the concomitant mitochondrial swelling and cristae disorganization in cardiac tissue of symptomatic cMKO mice (Fig. S3d, e), we sought to investigate whether MTFP1 loss specifically increased cell death sensitivity. Here, MTFP1 is linked to familial dilated cardiomyopathy.