FGFR1 and 2, the receptor of FGF2, were differently expressed in leukaemia cells co-cultured with MSCs from different origin and FGFR2 expression was significantly increased in leukaemia cells co-cultured with MSCs from T-ALL mice after PCR validation (Fig. 4E). This evidence concerns the gene FGFR1 and acute lymphoblastic leukemia.