Meanwhile, a significant negative correlation for mRNA expressions was found between GPR35 and CAPN10 based on the lasted study GC data (Pearson correlation, r = −0.84, p = 1.25e-3, Fig. 3B), indicating that the ERR event probably not only active GPR35 but also partly contribute to decreasing the expression level of CAPN10 in GC tumors. The gene discussed is GPR35; the disease is gastric cancer.