Interestingly, among the identified proteins some are known to be involved in tumorigenesis like mitogen-activated protein kinase 3 (MAPK3), protein kinase C alpha type (PRKCA) and some were already identified in glioblastoma e.g. CRMP1, DPYSL2 (i.e. CRMP2)26, DPYSL5 (i.e. CRMP5)27, GAP4328–30, as well as Tau protein encoded by MAPT in low-grade glioma31. Here, MAP3K3 is linked to glioblastoma.