Visualizing neutrophils spatially in BA, we found that FCN3+ neutrophils (cluster 5) specifically inhabited the fibrotic niche area (Figure 9C), and GO enrichment analysis showed that this subtype had BPs involved in ‘positive regulation of EGFR’ and ‘FGFR signaling pathway’ (Appendix S7), indicating they may promote liver fibrosis. The gene discussed is EGFR; the disease is Hepatic fibrosis.