PRDM1 and systemic lupus erythematosus: OAS2 and PRDM1 have been implicated in the Toll-like receptor (TLR) signalling pathway and SLE, respectively.33–35 Interestingly, the most significant potentially novel SNVs within the PRDM1 gene, which encodes B-lymphocyte-induced maturation protein 1 (BLIMP-1), are not in linkage disequilibrium (LD) with previously reported SLE-associated SNVs (rs548234 and rs6568431).