Immunofluorescence imaging using a confocal microscope determined the overall uptake of PKH-26–labeled HPSC sEVs (red) in normal and pancreatic cancer cells (Fig. 3, D and E) and uptake of HPaStec sEVs in panc1 and Miapaca2 cells (Fig. 3H). The gene discussed is PDXK; the disease is familial pancreatic carcinoma.