BTG2 and pachyonychia congenita: Compelling evidence obtained from another inquiry revealed that PC cell-derived exosomal miR-27a is linked with the angiogenesis of human microvascular endothelial cells via targeting BTG2, a protein involved in cell differentiation, apoptosis, antiproliferation, and DNA damage repair, and could be relevant for treating PC; nevertheless, further studies are required to fully understand the molecular crosstalk between this miRNA and angiogenic factors [139].