[194] used a KrasG12D; Pdx1-Cre mouse model to examine the miRNA expression level from the precursor lesions to the final stage of PC (which is PDAC), and they noticed that a wide range of miRNAs had different expression levels at 10, 30, 40, and 50 weeks of PC progression. Here, PDX1 is linked to pachyonychia congenita.