INS and type 2 diabetes mellitus: In subjects with T2DM not taking insulin sensitizers (metformin/thiazolidinediones), the serum SerpinB1 levels were positively correlated with QUICKI (β = 0.465, P = 0.047), and negatively correlated with T-Chol (β = -0.449, P = 0.012), LDL-Chol (β = -0.550, P = 0.002), and γGTP (β = -0.374, P = 0.039) after adjusting for age and sex (Model 1).