Kamal et al. [5] showed that serum SerpinB1 levels were significantly lower in T2DM subjects than in nondiabetic subjects, positively associated with C-peptide and homeostasis model assessment for β-cell function (HOMA2-%β), and negatively associated with fasting blood glucose (FBG), HbA1c, total cholesterol (T-Chol), and triglycerides (TG). The gene discussed is SERPINB1; the disease is type 2 diabetes mellitus.