For clarify the mechanism of anti-proliferation, we constructed a network of the KEGG enriched cellular signaling pathways (Hippo signaling pathways, TGF-beta signaling pathways, PI3K-Akt signaling pathway, p53 signaling pathway, cAMP signaling pathway) and Pathways in cancer with DEGs (Fig. 5). The gene discussed is AKT1; the disease is cancer.