RIGI and infectious disease: As depicted in Figure 2B, the upregulated DEGs were also significantly enriched in infectious diseases and pathways associated with innate immunity, such as Influenza A (22 genes), RIG-I-like signaling pathway (11 genes), Cytosolic DNA-sensing pathway (10 genes), PPAR (Peroxisome proliferator-activated receptors) signaling pathway (10 genes), Toll-like receptor signaling pathway (7 genes) and NF-κB signaling pathway (6 genes).