These cells promote the growth and chemoresistance of MM cells by inducing or secreting cytokines such as interleukin-6 (IL-6) (22), interleukin-10 (IL-10) (23), transforming growth factor-beta (TGF-β) (24), a proliferation-inducing ligand (APRIL) (25), and heat shock proteins (26). This evidence concerns the gene TNFSF13 and Miyoshi myopathy.