TRPM2 is overexpressed in cells from patients with acute myeloid leukemia (AML) and in AML cell lines (e.g. Kasumi-1, U937, KG-1, MV-4-11, SKNO1, THP-1, MonoMac-6, AML-193, MOLM13 and SHSY5Y) (129). The gene discussed is TRPM2; the disease is acute myeloid leukemia.