ABCB1 and colorectal carcinoma: To further validate that active β-catenin and MDR1 expressions in CRC cells are correlated with CD44v6 expression, we evaluated the effects of FOLFOX on expression of these proteins in SW480-S and SW480-FR cells following FOLFOX treatment with or without CD44v6 shRNA1, and CD44v6 shRNA2 (Figures 2D, E).