In addition, observed from the uterine corpus endometrial carcinoma (UCEC) dataset of The Cancer Genome Atlas database (TCGA) database (https://portal.gdc.cancer.gov/) and GEPIA (http://gepia.cancer-pku.cn/), the ESCRT-III components CHMP2A, CHMP4B, CHMP4C, CHMP5, and CHMP6 were significantly related to tumor-infiltrating lymphocytes (TILs), revealing that a deregulated ESCRT pathway would offer a potential target or effective markers in cancer immunotherapy. The gene discussed is CHMP4C; the disease is cancer.